Vaccine Ingredients
and
Manufacturer Information
(Listed in Alphabetical order by Vaccine)
The three main components to every vaccine are the ingredients, the process ingredients and the culture medium.
Vaccine Ingredients – are substances that appear in the final vaccine product
Process Ingredients – are substances used to create the vaccine that may or may not appear in the final vaccine product
Culture Media – are the substances used to grow the vaccine culture
Though not listed, each vaccine contains strains of the virus being vaccinated against.
To see the manufacturer’s package insert that contains information about dosage, ingredient quantity, and how the vaccine is made, please click on each vaccine’s Trade Name.
Some vaccines, like influenza vaccines, are modified frequently and you may wish to consult the package inserts online and your doctor for the most current information.
The vaccines shown below have been approved by the Food & Drug Administration (FDA) and commonly recommended by the Centers for Disease Control (CDC).
Controversial products used to make vaccines:
Human Fetal Lung Tissue Cells (WI-38)
1. Adenovirus Vaccine | ||
MANUFACTURER: Barr Labs Inc. | ||
PROPER NAME: Adenovirus Type 4 and Type 7 Vaccine, Live, Oral | TRADE NAME: -- ( Package Insert) | |
VACCINE INGREDIENTS | monosodium glutamate, sucrose, D-mannose, D-fructose, dextrose, human serum albumin, potassium phosphate, plasdone C, anhydrous lactose, microcrystalline cellulose, polacrilin potassium, magnesium stearate, cellulose acetate phthalate, alcohol, acetone, castor oil, FD&C Yellow #6 aluminum lake dye | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | human-diploid fibroblast cell cultures (WI-38), Dulbecco's Modified Eagle's Medium, fetal bovine serum, sodium bicarbonate | |
2. Anthrax Vaccine | ||
MANUFACTURER: Emergent BioDefense Operations Lansing LLC | ||
PROPER NAME: Anthrax Vaccine Adsorbed | TRADE NAME: Biothrax | |
VACCINE INGREDIENTS | aluminum hydroxide, sodium chloride, benzethonium chloride, formaldehyde, 83kDa protective antigen (PA) protein | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | amino acids, vitamins, inorganic salts and sugars
| |
3. BCG Vaccine | ||
MANUFACTURER: Organon Teknika Corp. | ||
PROPER NAME: BCG Live | TRADE NAME: Tice BCG | |
VACCINE INGREDIENTS | glycerin, asparagine, citric acid, potassium phosphate, magnesium sulfate, iron ammonium citrate, lactose | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | glycerin, asparagine, citric acid, potassium phosphate, magnesium sulfate, iron ammonium citrate
| |
4. Cholera Vaccine | ||
MANUFACTURER: Pax Vax Bermuda Ltd. | ||
PROPER NAME: Cholera Vaccine Live Oral | TRADE NAME: Vaxchora | |
VACCINE INGREDIENTS | ascorbic acid, hydrolyzed casein, sodium chloride, sucrose, dried lactose, sodium bicarbonate, sodium carbonate | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | casamino acids, yeast extract, mineral salts, anti-foaming agent
| |
5. DT Vaccine | ||
MANUFACTURER: Sanofi Pasteur, Inc. | ||
PROPER NAME: Diphtheria and Tetanus Toxoid Adsorbed | TRADE NAME: -- ( Package Insert) | |
VACCINE INGREDIENTS | aluminum phosphate, formaldehyde, aluminum phosphate, isotonic sodium chloride, formaldehyde | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | aluminum phosphate, isotonic sodium chloride solution, casein, cysteine, maltose, dextrose, uracil, inorganic salts, vitamins
| |
6. DTap Vaccine | ||
MANUFACTURER: Sanofi Pasteur, Ltd. | ||
PROPER NAME: Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed | TRADE NAME: Daptacel | |
VACCINE INGREDIENTS | aluminum phosphate, formaldehyde, glutaraldehyde, 2-Phenoxyethanol | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Stainer-Scholte medium, modified Mueller’s growth medium, modified Mueller-Miller casamino acid medium (without beef heart infusion), casamino acids, dimethyl-beta-cyclodextrin, ammonium sulfate, aluminum phosphate, formaldehyde | |
7. DTap Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed | TRADE NAME: Infanrix | |
VACCINE INGREDIENTS | formaldehyde, aluminum hydroxide, sodium chloride, polysorbate 80 (Tween 80) | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | formaldehyde, glutaraldehyde, Fenton medium (containing bovine extract), modified Latham medium (derived from bovine casein), modified Stainer-Scholte liquid medium, aluminum hydroxide | |
8. DTap-IPV Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine | TRADE NAME: Kinrix | |
VACCINE INGREDIENTS | formaldehyde, aluminum hydroxide, sodium chloride, polysorbate 80 (Tween 80), neomycin sulfate, polymyxin B | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | formaldehyde, glutaraldehyde, aluminum hydroxide, Vero cells, calf serum, lactalbumin hydrolysate, Fenton medium (containing bovine extract), modified Latham medium (derived from bovine casein), modified Stainer-Scholte liquid medium | |
9. DTap-IPV Vaccine | ||
MANUFACTURER: Sanofi Pasteur | ||
PROPER NAME: Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed and Inactivated Poliovirus Vaccine | TRADE NAME: Quadracel | |
VACCINE INGREDIENTS | formaldehyde, aluminum phosphate, 2-Phenoxyethanol, polysorbate 80, glutaraldehyde, neomycin, polymyxin B sulfate, bovine serum albumin | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | modified Mueller’s growth medium, ammonium sulfate, modified Mueller-Miller casamino acid medium (without beef heart infusion), aluminum phosphate, modified Stainer-Scholte medium (added casamino acids and dimethyl-beta-cyclodextrin), glutaraldehyde, formaldehyde, MRC-5 cells (with added Medium 199 without calf serum), CMRL 1969 medium (supplemented with calf serum) | |
10. DTap-HepB-IPV Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B (Recombinant) and Inactivated Poliovirus Vaccine Combined | TRADE NAME: Pediarix | |
VACCINE INGREDIENTS | formaldehyde, aluminum hydroxide, aluminum phosphate, sodium chloride, polysorbate 80 (Tween 80), neomycin sulfate, polymyxin B, yeast protein | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | formaldehyde, gluteraldehyde, aluminum hydroxide, aluminum phosphate, lactalbumin hydrolysate, calf serum, Fenton medium (containing bovine extract), modified Latham medium (derived from bovine casein), modified Stainer-Scholte liquid medium, Vero cells | |
11. DTap-IPV/Hib Vaccine | ||
MANUFACTURER: Sanofi Pasteur, Ltd. | ||
PROPER NAME: Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate) Vaccine | TRADE NAME: Pentacel | |
VACCINE INGREDIENTS | aluminum phosphate, polysorbate 80, sucrose, formaldehyde, glutaraldehyde, bovine serum albumin, 2-Phenoxyethanol, neomycin, polymyxin B sulfate | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | aluminum phosphate, formaldehyde, glutaraldehyde, 2-Phenoxyethanol, modified Mueller’s growth medium, Mueller-Miller casamino acid medium (without beef heart infusion), modified Stainer-Scholte medium (with added casamino acids, dimethyl-beta-cyclodextrin), MRC-5 cells, CMRL 1969 medium (supplemented with calf serum), ammonium sulfate, water, Medium 199 (without calf serum) | |
12. Hib Vaccine | ||
MANUFACTURER: Sanofi Pasteur, SA | ||
PROPER NAME: Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate) | TRADE NAME: ActHIB | |
VACCINE INGREDIENTS | sodium chloride, formaldehyde, sucrose | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | ammonium sulfate, Modified Mueller and Miller medium, saline diluent, formaldehyde, casein derivatives | |
13. Hib Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate) | TRADE NAME: Hiberix | |
VACCINE INGREDIENTS | formaldehyde, sodium chloride, lactose | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | formaldehyde, synthetic medium, semi-synthetic medium, saline diluent, lactose | |
14. Hib Vaccine | ||
MANUFACTURER: Merck Sharp & Dohme Corp. | ||
PROPER NAME: Haemophilus B Conjugate Vaccine (Meningococcal Protein Conjugate) | TRADE NAME: Liquid PedvaxHIB | |
VACCINE INGREDIENTS | amorphous aluminum hydroxyphosphate sulfate, sodium chloride | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | complex fermentation media, ethanol, phenol | |
15. Hep A Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Hepatitis A Vaccine, Inactivated | TRADE NAME: Havrix | |
VACCINE INGREDIENTS | MRC-5 cellular proteins, formalin, aluminum hydroxide, amino acid supplement, phosphate-buffered saline solution, polysorbate 20, neomycin sulfate, aminoglycoside antibiotic | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | ||
16. Hep A Vaccine | ||
MANUFACTURER: Merck & Co., Inc. | ||
PROPER NAME: Hepatitis A Vaccine, Inactivated | TRADE NAME: VAQTA | |
VACCINE INGREDIENTS | amorphous aluminum hydroxyphosphate sulfate, non-viral protein, DNA, bovine albumin, formaldehyde, neomycin, sodium borate, sodium chloride, other process chemical residuals | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Formalin, amorphous aluminum hydroxyphosphate sulfate, formaldehyde, neomycin, MRC-5 fibroblasts | |
17. Hep B Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Hepatitis B Vaccine (Recombinant) | TRADE NAME: Engerix-B | |
VACCINE INGREDIENTS | aluminum hydroxide, yeast protein, sodium chloride, disodium phosphate dihydrate, sodium dihydrogen phosphate dihydrate | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | ||
18. Hep B Vaccine | ||
MANUFACTURER: Merck & Co., Inc. | ||
PROPER NAME: Hepatitis B Vaccine (Recombinant) | TRADE NAME: Recombivax HB | |
VACCINE INGREDIENTS | formaldehyde, potassium aluminum sulfate, amorphous aluminum hydroxyphosphate sulfate, yeast protein | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | yeast protein, soy peptone, dextrose, amino acids, mineral salts, alum (potassium aluminum sulfate), amorphous aluminum hydroxyphosphate sulfate, formaldehyde | |
19. Hep B Vaccine | ||
MANUFACTURER: Dynavax Technologies Corporation | ||
PROPER NAME: Hepatitis B Vaccine (Recombinant), Adjuvanted | TRADE NAME: Heplisav-B | |
VACCINE INGREDIENTS | yeast protein, yeast DNA, deoxycholate, phosphorothioate linked oligodeoxynucleotide, sodium phosphate, dibasic dodecahydrate, sodium chloride, monobasic dehydrate, polysorbate 80 | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | vitamins and mineral salts | |
20. Hep A/Hep B Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Hepatitis A Inactivated & Hepatitis B (Recombinant) Vaccine | TRADE NAME: Twinrix | |
VACCINE INGREDIENTS | MRC-5 human diploid cells, formalin, aluminum phosphate, aluminum hydroxide, amino acids, sodium chloride, phosphate buffer, polysorbate 20, neomycin sulfate, yeast protein, water | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Genetically engineered yeast protein, MRC-5 human diploid cells, aluminum salts | |
21. Human Papillomavirus | ||
MANUFACTURER: Merck & Co., Inc. | ||
PROPER NAME: Human Papillomavirus 9-valent Vaccine, Recombinant | TRADE NAME: Gardasil 9 | |
VACCINE INGREDIENTS | amorphous aluminum hydroxyphosphate sulfate, sodium chloride, L-histidine, polysorbate 80, sodium borate, yeast protein, water | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | vitamins, amino acids, mineral salts, carbohydrates, yeast cells, aluminum-containing adjuvant (Amorphous Aluminum Hydroxyphosphate Sufate) | |
22. Influenza Vaccine | ||
MANUFACTURER: Seqirus Pty. Ltd. | ||
PROPER NAME: Influenza Virus Vaccine | TRADE NAME: Afluria (Trivalent) | |
VACCINE INGREDIENTS | sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, monobasic potassium phosphate, potassium chloride, calcium chloride, sodium taurodeoxycholate, ovalbumin, sucrose, neomycin sulfate, polymyxin B, beta-propiolactone, Thimerosal (multi-dose vials) | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | beta-propiolactone, sodium taurodeoxycholate, allantoic fluid of embryonated chicken eggs, sucrose density gradient, phosphate buffered isotonic solution | |
23. Influenza Vaccine | ||
MANUFACTURER: Seqiris, Inc. | ||
PROPER NAME: Influenza Vaccine, Adjuvanted | TRADE NAME: Fluad (Trivalent) | |
VACCINE INGREDIENTS | squalene, polysorbate 80, sorbitan trioleate, sodium citrate dehydrate, citric acid monohydrate, neomycin, kanamycin, barium, hydrocortisone, egg proteins, cetyltrimethylammonium bromide (CTAB), formaldehyde | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | allantoic cavity of embryonated hen's eggs, MF59C.1 adjuvant (MF59), formaldehyde, cetyltrimethylammonium bromide (CTAB) | |
24. Influenza Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Influenza Virus Vaccine | TRADE NAME: Fluarix Quadrivalent | |
VACCINE INGREDIENTS | octoxynol-10 (TRITON X-100), α-tocopheryl hydrogen succinate, polysorbate 80 (Tween 80), hydrocortisone, gentamicin sulfate, ovalbumin, formaldehyde, sodium deoxycholate, sodium phosphate-buffered isotonic sodium chloride | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | embryonated chicken eggs, linear sucrose density gradient solution (containing detergent), sodium deoxycholate, formaldehyde, sodium phosphate buffered isotonic sodium chloride solution | |
25. Influenza Vaccine | ||
MANUFACTURER: Protein Sciences Corporation | ||
PROPER NAME: Influenza Vaccine | TRADE NAME: Flublok (Quadrivalent) | |
VACCINE INGREDIENTS | sodium chloride, monobasic sodium phosphate, dibasic sodium phosphate, polysorbate 20 (Tween 20), baculovirus and Spodoptera frugiperda cell proteins, baculovirus and cellular DNA, Triton X-100 | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | HA insect cell (fall armyworm, Spodoptera frugiperda) proteins, lipids, vitamins, amino acids, mineral salts, Triton X-100 | |
26. Influenza Vaccine | ||
MANUFACTURER: Seqiris, Inc. | ||
PROPER NAME: Influenza Vaccine | TRADE NAME: Flucelvax (Quadrivalent) | |
VACCINE INGREDIENTS | Madin Darby Canine Kidney (MDCK) cell protein, phosphate buffered saline, protein other than HA, MDCK cell DNA, polysorbate 80, cetyltrimethlyammonium bromide, and β- propiolactone, Thimerosal (multi-dose vials) | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Madin Darby Canine Kidney (MDCK) cells, B-propiolactone, cetyltrimethylammonium bromide, phosphate buffered saline | |
27. Influenza Vaccine | ||
MANUFACTURER: ID Biomedical Corporation of Quebec | ||
PROPER NAME: Influenza Virus Vaccine | TRADE NAME: FluLaval (Quadrivalent) | |
VACCINE INGREDIENTS | ovalbumin, formaldehyde, sodium deoxycholate, α-tocopheryl hydrogen succinate, polysorbate 80, Thimerosal (multi-dose vials), phosphate-buffered saline solution | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | allantoic cavity of embryonated hens' eggs, formaldehyde, sodium deoxycholate | |
28. Influenza Vaccine | ||
MANUFACTURER: Sanofi Pasteur, Inc. | ||
PROPER NAME: Influenza Virus Vaccine | TRADE NAME: Fluzone (Quadrivalent) | |
VACCINE INGREDIENTS | formaldehyde, egg protein, octylphenol ethoxylate (Triton X-100), sodium phosphate- buffered isotonic sodium chloride solution, Thimerosal (multi-dose vials) | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | embryonated chicken eggs, allantoic fluid, formaldehyde, linear sucrose density gradient solution, non-ionic surfactant Octylphenol Ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, | |
29. Influenza | ||
MANUFACTURER: Sanofi Pasteur, Inc. | ||
PROPER NAME: Influenza Virus Vaccine | TRADE NAME: Fluzone: High Dose | |
VACCINE INGREDIENTS | egg protein, octylphenol ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | embryonated chicken eggs, formaldehyde linear sucrose density gradient solution, Octylphenol Ethoxylate (Triton X-100), sodium phosphate-buffered isotonic sodium chloride solution, | |
30. Influenza Vaccine | ||
MANUFACTURER: MedImmune, LLC | ||
PROPER NAME: Influenza Virus Vaccine Live, Intranasal | TRADE NAME: FluMist Quadrivalent | |
VACCINE INGREDIENTS | monosodium glutamate, hydrolyzed porcine gelatin, arginine, sucrose, dibasic potassium phosphate, monobasic potassium phosphate, ovalbumin, gentamicin sulfate, ethylenediaminetetraacetic acid (EDTA) | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | SPF (specific pathogen-free) eggs, stabilizing buffer, sucrose, potassium phosphate | |
31. Japanese Encephalitis Vaccine | ||
MANUFACTURER: Valneva Austria GmbH | ||
PROPER NAME: Japanese Encephalitis Vaccine, Inactivated, Adsorbed | TRADE NAME: Ixiaro | |
VACCINE INGREDIENTS | aluminum hydroxide, protamine sulfate, formaldehyde, bovine serum albumin, Vero cell DNA, sodium metabisulphite, Vero cell protein | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Vero cells, protamine sulfate, formaldehyde, | |
32. Meningococcal Vaccine | ||
MANUFACTURER: Sanofi Pasteur Inc. | ||
PROPER NAME: Meningococcal (Groups A, C, Y, and W-135) Oligosaccharide Diphtheria Toxoid Conjugate Vaccine | TRADE NAME: Menactra | |
VACCINE INGREDIENTS | sodium phosphate-buffered isotonic sodium chloride solution, formaldehyde, diphtheria toxoid | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Mueller Hinton agar, Watson Scherp media (containing casamino acid), formaldehyde, ammonium sulfate, modified culture medium (containing hydrolyzed casein) | |
33. Meningococcal Vaccine | ||
MANUFACTURER: Novartis Vaccines and Diagnostics, Inc. | ||
PROPER NAME: Meningococcal (Groups A, C, Y, and W-135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine | TRADE NAME: Menveo | |
VACCINE INGREDIENTS | formaldehyde, CRM197 protein | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Franz Complete medium, formaldehyde, CY medium (contains yeast extracts and amino acids), purified polysaccharides, CRM197 protein | |
34. Meningococcal Vaccine | ||
MANUFACTURER: Novartis Vaccines and Diagnostics, Inc. | ||
PROPER NAME: Meningococcal Group B Vaccine | TRADE NAME: Bexsero | |
VACCINE INGREDIENTS | aluminum hydroxide, sodium chloride, histidine, sucrose, kanamycin | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | factor H binding protein (fHbp), Outer Membrane Vesicles (OMV), aluminum hydroxide, sodium chloride, histidine, sucrose, Escherichia coli (E. coli), deoxycholate | |
35. Meningococcal Vaccine | ||
MANUFACTURER: Wyeth Pharmaceuticals, Inc. | ||
PROPER NAME: Meningococcal Group B Vaccine | TRADE NAME: Trumenba | |
VACCINE INGREDIENTS | polysorbate 80, aluminum phosphate, histidine buffered saline | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | E. coli, defined fermentation growth media, polysorbate 80 (PS80) | |
36. MMR Vaccine | ||
MANUFACTURER: Merck and Co., Inc. | ||
PROPER NAME: Measles, Mumps, and Rubella Virus Vaccine, Live | TRADE NAME: M-M-R-II | |
VACCINE INGREDIENTS | vitamins, amino acids, fetal bovine serum, sucrose, glutamate, recombinant human albumin, neomycin, sorbitol, hydrolyzed gelatin, sodium phosphate, sodium chloride | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | chick embryo cell culture, WI-38 human diploid lung fibroblasts, Medium 199 (containing vitamins, amino acids, fetal bovine serum, SPGA (sucrose, phosphate, glutamate, recombinant human albumin), neomycin, Minimum Essential Medium (containing vitamins, amino acids, fetal bovine serum, recombinant human albumin, neomycin), sorbitol, hydrolyzed gelatin stabilizer | |
37. MMRV (Frozen: Recombinant Albumin) | ||
MANUFACTURER: Merck and Co., Inc. | ||
PROPER NAME: Measles, Mumps, Rubella and Varicella Virus Vaccine Live | TRADE NAME: ProQuad Frozen Formulation | |
VACCINE INGREDIENTS | MRC-5 cells including DNA and protein, sucrose, hydrolyzed gelatin, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate dibasic, recombinant human albumin, sodium bicarbonate, potassium phosphate monobasic, potassium chloride; potassium phosphate dibasic, neomycin, bovine calf serum | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, bovine serum, recombinant human albumin | |
38. MMRV (Frozen: Human Serum Albumin) | ||
MANUFACTURER: Merck and Co., Inc. | ||
PROPER NAME: Measles, Mumps, Rubella and Varicella Virus Vaccine Live | TRADE NAME: ProQuad Frozen: Human Serum Albumin | |
VACCINE INGREDIENTS | MRC-5 cells including DNA and protein, sucrose, hydrolyzed gelatin, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate dibasic, human albumin, sodium bicarbonate, potassium phosphate monobasic, potassium chloride; potassium phosphate dibasic, neomycin, bovine calf serum | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, bovine serum, recombinant | |
39. MMRV (Refrigerator Stable) | ||
MANUFACTURER: Merck and Co., Inc. | ||
PROPER NAME: Measles, Mumps, Rubella and Varicella Virus Vaccine Live | TRADE NAME: ProQuad, Refrigerator Stable Formulation | |
VACCINE INGREDIENTS | MRC-5 cells including DNA and protein, sucrose, hydrolyzed gelatin, urea, sodium chloride, sorbitol, monosodium L-glutamate, sodium phosphate dibasic, recombinant human albumin, sodium bicarbonate, potassium phosphate , potassium chloride, neomycin, bovine serum albumin | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | chick embryo cell culture, WI-38 human diploid lung fibroblasts, MRC-5 cells, bovine serum, recombinant human albumin | |
40. Pneumococcal Vaccine | ||
MANUFACTURER: Wyeth Pharmaceuticals, Inc. | ||
PROPER NAME: Pneumococcal 13-valent Conjugate Vaccine (Diphtheria CRM197 Protein) | TRADE NAME: Prevnar 13 | |
VACCINE INGREDIENTS | CRM197 carrier protein, polysorbate 80, succinate buffer, aluminum phosphate | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | soy peptone broth, casamino acids and yeast extract-based medium, ammonium sulfate, CRM 197 | |
41. Pneumococcal Vaccine | ||
MANUFACTURER: Merck & Co., Inc. | ||
PROPER NAME: Pneumococcal Vaccine, Polyvalent | TRADE NAME: Pneumovax-23 | |
VACCINE INGREDIENTS | phenol | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | ----- | |
42. Polio Vaccine | ||
MANUFACTURER: Sanofi Pasteur, SA | ||
PROPER NAME: Poliovirus Vaccine Inactivated (Monkey Kidney Cell) | TRADE NAME: IPOL | |
VACCINE INGREDIENTS | calf bovine serum albumin, 2-Phenoxyethanol, formaldehyde, neomycin, streptomycin, polymyxin B, M-199 medium | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Vero cells, Eagle MEM modified medium, newborn calf bovine serum, M-199 (without calf bovine serum) | |
43. Rabies Vaccine | ||
MANUFACTURER: Sanofi Pasteur, SA | ||
PROPER NAME: Rabies Vaccine | TRADE NAME: IMOVAX | |
VACCINE INGREDIENTS | human albumin, neomycin sulfate, phenol red, beta-propiolactone | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | MRC-5 cells, beta-propiolactone | |
44. Rabies Vaccine | ||
MANUFACTURER: Novartis Vaccines and Diagnostics | ||
PROPER NAME: Rabies Vaccine | TRADE NAME: RabAvert | |
VACCINE INGREDIENTS | chicken protein, polygeline (processed bovine gelatin), human serum albumin, potassium glutamate, sodium EDTA, ovalbumin, neomycin, chlortetracycline, amphotericin B | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | chicken fibroblasts, synthetic cell culture medium (with added human albumin), polygeline (processed bovine gelatin), antibiotics, B-propiolactone, sucrose density-gradient, buffered polygeline, potassium glutamate | |
45. Rotavirus Vaccine | ||
MANUFACTURER: Merck & Co., Inc. | ||
PROPER NAME: Rotavirus Vaccine, Live, Oral, Pentavalent | TRADE NAME: RotaTeq | |
VACCINE INGREDIENTS | sucrose, sodium citrate, sodium phosphate monobasic monohydrate, sodium hydroxide, polysorbate 80, cell culture media, fetal bovine serum [DNA from porcine circoviruses (PCV) 1 and 2 has been detected in RotaTeq. PCV-1 and PCV-2 are not known to cause disease in humans.] | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Vero cells, buffered stabilizer, porcine-derived material | |
46. Rotavirus Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Rotavirus Vaccine, Live, Oral | TRADE NAME: Rotarix | |
VACCINE INGREDIENTS | Dextran, Dulbecco’s Modified Eagle Medium (sodium chloride, potassium chloride, magnesium sulfate, ferric (III) nitrate, sodium phosphate, sodium pyruvate, D-glucose, concentrated vitamin solution, L-cystine, L-tyrosine, amino acids, L-glutamine, calcium chloride, sodium hydrogenocarbonate, and phenol red), sorbitol, sucrose, calcium carbonate, sterile water, xanthan [Porcine circovirus type 1 (PCV-1) is present in Rotarix. PCV-1 is not known to cause disease in humans.] | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Vero cells, porcine-derived materials, amino acids, dextran, Dulbecco's Modified Eagle Medium (sodium chloride, potassium chloride, magnesium sulfate, ferric (III) nitrate, sodium phosphate, sodium pyruvate, D-glucose, concentrated vitamin solution, L-cystine, L-tyrosine, amino acids solution, L-glutamine, calcium chloride, sodium hydrogenocarbonate, phenol red), sorbitol, sucrose | |
47. Smallpox Vaccine | ||
MANUFACTURER: Emergent Product Development Gaithersburg, Inc. | ||
PROPER NAME: Smallpox (Vaccinia) Vaccine, Live | TRADE NAME: ACAM2000 | |
VACCINE INGREDIENTS | HEPES, 2% human serum albumin, 0.5 - 0.7% sodium chloride USP, 5% Mannitol USP, neomycin, polymyxin B, 50% Glycerin USP, 0.25% phenol USP | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Vero cells, human serum albumin, sodium chloride, mannitol, neomycin, polymyxin B, Dryvax | |
48. TD Vaccine | ||
MANUFACTURER: Sanofi Pasteur, Ltd., License #1726 | ||
PROPER NAME: Tetanus and Diphtheria Toxoids Adsorbed For Adult Use | TRADE NAME: TENIVAC | |
VACCINE INGREDIENTS | aluminum phosphate, formaldehyde, ammonium sulfate, sodium chloride, water | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | modified Mueller-Miller casamino acid medium (without beef heart infusion), formaldehyde, ammonium sulfate, modified Mueller’s growth medium, aluminum phosphate | |
49. TD Vaccine | ||
MANUFACTURER: Mass Biologics | ||
PROPER NAME: Tetanus and Diphtheria Toxoids, Adsorbed | TRADE NAME: TDVAX | |
VACCINE INGREDIENTS | ||
Substances used to create and grow the vaccine, which may or may not appear in the final product | modified Mueller's media (contains bovine extracts), formaldehyde, ammonium sulfate, aluminum phosphate | |
50. Tdap Vaccine | ||
MANUFACTURER: Sanofi Pasteur, Ltd. | ||
PROPER NAME: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed | TRADE NAME: Adacel | |
VACCINE INGREDIENTS | aluminum phosphate, formaldehyde, 2-Phenoxyethanol, glutaraldehyde | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | modified Stainer-Scholte medium (added casamino acid, dimethyl-beta-cyclodextrin), glutaraldehyde, formaldehyde, aluminum phosphate, modified Mueller-Miller casamino acid medium (without beef heart infusion), ammonium sulfate, 2-Phenoxyethanol, water for injection | |
51. Tdap Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed | TRADE NAME: Boostrix | |
VACCINE INGREDIENTS | formaldehyde, aluminum hydroxide, sodium chloride, polysorbate 80 | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | modified Latham medium derived from bovine casein, Fenton medium (containing bovine extract), formaldehyde, modified Stainer-Scholte liquid medium, glutaraldehyde, aluminum hydroxide | |
52. Typhoid Vaccine | ||
MANUFACTURER: Sanofi Pasteur SA | ||
PROPER NAME: Typhoid Vi Polysaccharide Vaccine | TRADE NAME: Typhim Vi | |
VACCINE INGREDIENTS | formaldehyde, phenol, polydimethylsiloxane, disodium phosphate, monosodium phosphate, sodium chloride, sterile water | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | semi-synthetic medium, hexadecyltrimethylammonium bromide | |
53. Typhoid Vaccine | ||
MANUFACTURER: Berna Biotech, Ltd. | ||
PROPER NAME: Typhoid Vaccine Live Oral Ty21a | TRADE NAME: Vivotif | |
VACCINE INGREDIENTS | sucrose, ascorbic acid, amino acids, lactose, magnesium stearate. gelatin | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | yeast extract, casein, dextrose, and galactose, sucrose, ascorbic acid, amino acids, lyophilized bacteria, lactose, magnesium stearate | |
54. Varicella Vaccine | ||
MANUFACTURER: Merck & Co., Inc. | ||
PROPER NAME: Varicella Virus Vaccine, Live | TRADE NAME: Varivax, Frozen | |
VACCINE INGREDIENTS | MRC-5 human diploid cells, including DNA & protein, sucrose, hydrolyzed gelatin, sodium chloride, monosodium L-glutamate, sodium phosphate dibasic, sodium phosphate monobasic, potassium phosphate monobasic, potassium chloride, EDTA, neomycin, fetal bovine serum | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | human embryonic lung cell cultures, embryonic guinea pig cell cultures, WI-38 human diploid cell cultures, MRC-5 human diploid cell cultures, sucrose, phosphate, glutamate, processed gelatin | |
55. Varicella Vaccine | ||
MANUFACTURER: Merck & Co., Inc. | ||
PROPER NAME: Varicella Virus Vaccine, Live | TRADE NAME: Varivax, Refigerated | |
VACCINE INGREDIENTS | MRC-5 human diploid cells, including DNA & protein, sucrose, hydrolyzed gelatin, sodium chloride, monosodium L-glutamate, urea, sodium phosphate dibasic, potassium phosphate monobasic, potassium chloride, neomycin, bovine calf serum | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | human embryonic lung cell cultures, embryonic guinea pig cell cultures, WI-38 human diploid cell cultures, MRC-5 human diploid cell cultures, sucrose, phosphate, glutamate, processed gelatin, urea | |
56. Yellow Fever Vaccine | ||
MANUFACTURER: Sanofi Pasteur, Inc. | ||
PROPER NAME: Yellow Fever Vaccine | TRADE NAME: YF-Vax | |
VACCINE INGREDIENTS | sorbitol, gelatin, sodium chloride, egg protein | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | ||
57. Zoster Vaccine | ||
MANUFACTURER: Merck & Co., Inc. | ||
PROPER NAME: Zoster Vaccine, Live | TRADE NAME: Zostavax, Frozen | |
VACCINE INGREDIENTS | MRC-5 human diploid cells, including DNA & protein, sucrose, hydrolyzed porcine gelatin, sodium chloride, monosodium L-glutamate, sodium phosphate dibasic, potassium phosphate monobasic, potassium chloride; neomycin, bovine calf serum | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | ----- | |
58. Zoster Vaccine | ||
MANUFACTURER: Merck & Co., Inc. | ||
PROPER NAME: Zoster Vaccine, Live | TRADE NAME: Zostavax, Refrigerator Stable | |
VACCINE INGREDIENTS | MRC-5 human diploid cells, including DNA & protein, sucrose, hydrolyzed porcine gelatin, urea sodium chloride, monosodium L-glutamate, sodium phosphate dibasic, potassium phosphate monobasic, potassium chloride; neomycin, bovine calf serum | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | ----- | |
59. Zoster Vaccine | ||
MANUFACTURER: GlaxoSmithKline Biologicals | ||
PROPER NAME: Zoster Vaccine Recombinant, Adjuvanted | TRADE NAME: Shingrix | |
VACCINE INGREDIENTS | sucrose, sodium chloride, dioleoyl phosphatidylcholine (DOPC), 3-O-desacl-4’monophosphoryl lipid A (MPL), QS-21 (a saponin purified from plant extract Quillaja saponaria Molina), potassium dihydrogen phosphate, cholesterol, sodium dihydrogen phosphate dihydrate, disodium phosphate anhydrous, dipotassium phosphate, polysorbate 80, host cell protein and DNA | |
Substances used to create and grow the vaccine, which may or may not appear in the final product | Amino acids, dioleoyl phosphatidylcholine (DOPC), phosphate-buffered saline solution, disodium phosphate anhydrous, potassium dihydrogen phosphate, sodium chloride, water | |
GLOSSARY AND DETAILS FOR INGREDIENTS | |
Product | Possible Ingredients |
2-Phenoxyethanol | 2-Phenoxyethanol is a glycol ether used as a preservative in vaccines. It is a central nervous system depressant. |
Aluminum | Aluminum is used in vaccines as an adjuvant, which helps the vaccine work more quickly and more powerfully. Aluminum hydroxide, aluminum phosphate, and aluminum salts - Neurotoxin. Carries risk for long term brain inflammation/swelling, neurological disorders, autoimmune disease, Alzheimer's, dementia, and autism. It penetrates the brain where it persists indefinitely. |
Bovine casein | A casein is a family of phosphoproteins commonly found in mammalian milk. 80% of the proteins in cow's milk are casein. |
Bovine serum | Bovine "[s]erum is the centrifuged fluid component of either clotted or defibrinated whole blood. Bovine serum comes from blood taken from domestic cattle. Serum from other animals is also collected and processed but bovine serum is processed in the greatest volume." |
Chicken Eggs | Viruses can be grown in chicken eggs before being used in vaccinations. |
CMRL-1969 | L-alanine, L-arginine (free base)b, L-aspartic acid, L-cysteine-HCL, L-cystine, L-glutamic acid-H20, L-glutamine, glycine, L-histidine (free base)b, L-hydroxyproline, L-isoleucine, L-leucine, L-lysine, L-methionine, L-phenylalanine, L-proline, L-serine, L-threonine, L-tryptophan, L-tyrosine, L-valine, p-aminobenzoic acid, ascorbic acid, d-biotin, calcium pantothenate, cholesterol, choline chloride, ethanol, folic acid, glutathione, i-inositol, menadione, nicotinamide, nicotinic acid, pyridoxal-HCL, pyridoxine-HCL, riboflavine, riboflavine-5-phosphate, sodium acetate-3H2O, thiamine-HCL, Tween 80, vitamin A acetate, vitamin D (calciferol), vitamin E (a-tocopherol phosphate), D-glucose, phenol red, sodium chloride, potassium chloride, calcium chloride, magnesium culphate heptahydrate, sodium phosphate dibasic, sodium dihydrogen phosphate, monopotassium phosphate, sodium bicarbonate, iron nitrate nonahydrate |
Dulbecco's Modified Eagle's Serum | glucose, sodium bicarbonate, L-glutamine, pyridoxine HCl, pyridocal HCl, folic acid, phenol red, HEPES (2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid), L-methionine, L-cystine, sodium phosphate mono-basic, sodium pyruvate, vitamins |
Earle's Balanced Salt Medium | inorganic salts, D-glucose, phenol red, calcium, magnesium salts |
Fenton Medium | bovine extract |
Formaldehyde | Formaldehyde is used in vaccines to inactivate the virus so the person being inoculated does not contract the disease. Highly toxic systematic poison and carcinogen. |
Human albumin | Human albumin is a blood plasma protein produced in the liver that, among other functions, transports hormones, fatty acids, and other compounds, and buffers pH. |
Insect Cells | Cabbage moth and fall armyworm cells are used to grow viruses for vaccines. |
Latham Medium | bovine casein |
MDCK (Madin-Carby canine kidney cells) | cells from normal female adult Cocker Spaniel (harvested in 1958 by SH Madin and NB Darby), EMEM(EBSS) (Eagle's Minimum Essential Medium with Earle's Balanced Salt Solution), glutamine, non-essential amino acids, fetal bovine serum |
Mouse Brains | Live mice brains are inoculated with the Japanese encephalitis virus to grow the virus used in the vaccine. |
MRC-5 | Medical Research Council 5, human diploid cells (cells containing two sets of chromosomes) derived from the normal lung tissues of a 14-week-old male fetus aborted for "psychiatric reasons" in 1966 in the United Kingdom, Eagle's Basal Medium in Earle's balanced salt solution with bovine serum. Foreign DNA has the ability to interact with our own. |
Mueller Hinton Agar | Beef extract, acid hydrolysate of casein, starch, agar. Müller-Hinton agar is a microbiological growth medium that is commonly used for antibiotic susceptibility testing. |
Mueller-Miller Medium | glucose, sodium chloride, sodium phosphate dibasic, monopotassium, phosphate, magnesium sulfate hydrate, ferrous sulfate heptaphydrate, cystine hydrochloride, tyrosine hydrochloride, urasil hydrochloride, Ca-pantothenate in ethanol, thiamine in ethanol, pyridoxin-hydrochloride in ethanol, riboflavin in ethanol, biotin in ethanol, sodium hydroxide, beef heart infusion (de-fatted beef heart and distilled water), casein solution |
Polysorbate 80 | Also called Tween 80, Alkest 80, or Canarcel 80 (brand names). Polysorbate 80 is used as an excipient (something to basically thicken a vaccine for proper dosing) and an emulsifier (something to bond the ingredients). Trespasses the Blood-Brain Barrier and carries with it aluminum, thimerosal, and viruses; allowing it to enter the brain. |
Porcine gelatin | Gelatin is used to protect viruses in vaccines from freeze-drying or heat and to stabilize vaccines so they stay stable. |
Stainer-Scholte Liquid Medium | tris hydrochloride, tris base, glutamate (monosodium salt), proline, salt, monopotassium phosphate, potassium chloride, magnesium chloride, calcium chloride, ferrous sulfate, ascorbic acid, niacin, glutathione |
Thimerosal | Thimerosal is an organomercury compound used as a preservative. Neurotoxin. Induces cellular damage, reduces oxidation-reduction activity, cellular degeneration, and cell death. Linked to neurological disorders, Alzheimer's, dementia, and autism. |
Vero Cells (African Green Monkey Cells) | cells derived from the kidney of a normal, adult African Green monkey in 1962 by Y. Yasumura and Y. Kawakita Can carry the SV-40 cancer-causing virus that has already tainted about 30 million Americans. |
WI-38 human diploid cells | Winstar Institute 38, human diploid lung fibroblasts derived from the lung tissues of a female fetus aborted because the family felt they had too many children in 1964 in the United States. Foreign DNA has the ability to interact with our own. |
SOURCES
|
Vaccine Excipient Summary - Excipients Included in U.S. Vaccines, by Vaccine: https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/b/excipient-table-2.pdf
Vaccines Licensed for Use in the United States: https://www.fda.gov/vaccines-blood-biologics/vaccines/vaccines-licensed-use-united-states
Vero Cell Line Profile: https://admin.phe-culturecollections.org.uk/media/122249/vero-cell-line-profile.pdf
Latest Discussions